BDBM505240 US11066409, Compound I-0104::US11066409, Compound I-0110

SMILES COc1ccc(Nc2nc(=O)cc3N(C)CC(c4ccccc4)n23)c(C)c1

InChI Key InChIKey=JAAMCAUPBNSCFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 505240   

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505240(US11066409, Compound I-0110 | US11066409, Compound...)
Affinity DataIC50: 55nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505240(US11066409, Compound I-0110 | US11066409, Compound...)
Affinity DataIC50: 10nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2021
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
Shionogi

US Patent
LigandPNGBDBM505240(US11066409, Compound I-0110 | US11066409, Compound...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed