BDBM50523916 CHEMBL4461512

SMILES CC(C)c1cc(on1)C(=O)NC[C@H]1CCN(CCc2ccc(C)c(c2)C(F)(F)F)C1

InChI Key InChIKey=MSAAXPJRLXKNHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523916   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50523916(CHEMBL4461512)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as suppression of KCl-evoked current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50523916(CHEMBL4461512)
Affinity DataIC50: 7.61E+3nMAssay Description:Inhibition of Cav3.2 (unknown origin) assessed as suppression of KCl-evoked current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50523916(CHEMBL4461512)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed