BDBM50523867 CHEMBL4435790

SMILES COc1ccc(cc1OC)-c1coc(n1)-c1cc(OC(F)(F)F)ccc1-n1cncn1

InChI Key InChIKey=BALOOAJRLWUXJH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523867   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523867(CHEMBL4435790)
Affinity DataIC50: 7.63E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523867(CHEMBL4435790)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523867(CHEMBL4435790)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed