BDBM50523863 CHEMBL4552061

SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cccn1

InChI Key InChIKey=PRBIHULYVOZYOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523863   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523863(CHEMBL4552061)
Affinity DataIC50: 2.04E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523863(CHEMBL4552061)
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523863(CHEMBL4552061)
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed