BDBM50523668 CHEMBL4550603

SMILES COc1ccc(Cn2c3c(cnc4ccc(cc34)-c3cnc(OC)c(NS(C)(=O)=O)c3)n(C)c2=O)cc1

InChI Key InChIKey=KABBATBNPHTWDK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523668   

LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 42nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 289nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 580nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 241nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed