BDBM50523667 CHEMBL4560054
SMILES COc1ccc(Cn2c3cnc4ccc(cc4c3n(C)c2=O)-c2cnc(OC)c(NS(C)(=O)=O)c2)cc1
InChI Key InChIKey=MIXCNAMMWZBDMS-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50523667
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataIC50: 891nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair