BDBM50523664 CHEMBL4454741

SMILES COc1ccc(Cn2c3cnc4ccc(cc4c3n(C)c2=O)-c2cnc3ccccc3c2)cc1

InChI Key InChIKey=HVYJBSUHDFURHA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523664   

LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 38nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 342nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 421nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 676nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed