BDBM50523506 CHEMBL4472026

SMILES OC[C@H]1CCCN1Cc1ccc(COc2cccc(CCc3ccccc3)c2)cc1

InChI Key InChIKey=OETCYVILHFTAQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523506   

TargetSphingosine kinase 2(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50523506(CHEMBL4472026)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged SK2 expressed in baculovirus infected Sf9 insect cells using Sph as substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50523506(CHEMBL4472026)
Affinity DataIC50: 26nMAssay Description:Inhibition of GFP-tagged SK1 (unknown origin) expressed in HEK293 cells using Sph as substrate measured after 30 mins in presence of [gamma32P]ATP by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed