BDBM50523479 CHEMBL4436479

SMILES Cc1cccc(NC(=O)CN2CCC(CC2)c2ccc(Cl)cc2)c1

InChI Key InChIKey=MGAAMGRSXKBQAO-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50523479   

TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataKi:  2.63E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataIC50: 4.24E+4nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataIC50: 7.02E+4nMAssay Description:Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataIC50: 7.14E+4nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Rowan University

Curated by ChEMBL
LigandPNGBDBM50523479(CHEMBL4436479)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human D2L receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed