BDBM50523392 CHEMBL4582203

SMILES COc1ccc2nc3CCCCc3c(NCCCCCCCCNC(=O)[C@@H](N)Cc3c[nH]c4ccccc34)c2c1

InChI Key InChIKey=BMKLRTWRKHBPOD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523392   

TargetNitric oxide synthase, endothelial(Rat)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523392(CHEMBL4582203)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523392(CHEMBL4582203)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523392(CHEMBL4582203)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed