BDBM50523388 CHEMBL4556575

SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=CYZAREYILAFECL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523388   

TargetCholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523388(CHEMBL4556575)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed