BDBM50523385 CHEMBL4475391

SMILES COc1ccc2nc3CCCCc3c(NCCCCNC(=O)[C@@H](N)Cc3c[nH]c4ccccc34)c2c1

InChI Key InChIKey=YUYUQINXUWCCQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523385   

TargetCholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523385(CHEMBL4475391)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523385(CHEMBL4475391)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523385(CHEMBL4475391)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed