BDBM50523381 CHEMBL4444822

SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=LNSAIWZSMKGWEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50523381   

TargetAcetylcholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523381(CHEMBL4444822)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523381(CHEMBL4444822)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50523381(CHEMBL4444822)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed