BDBM50523347 CHEMBL4470416

SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CCC1=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=RCMFZCLVTRBJDF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523347   

TargetCarbonic anhydrase 9(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523347(CHEMBL4470416)
Affinity DataKi:  6nMAssay Description:Inhibition of membrane bound human CA 9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523347(CHEMBL4470416)
Affinity DataKi:  67nMAssay Description:Inhibition of membrane bound human CA 12 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523347(CHEMBL4470416)
Affinity DataKi:  74nMAssay Description:Inhibition of human cytosolic CA 2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Saint Petersburg State University

Curated by ChEMBL
LigandPNGBDBM50523347(CHEMBL4470416)
Affinity DataKi:  5.96E+3nMAssay Description:Inhibition of human cytosolic CA 1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed