BDBM50523303 CHEMBL4472170

SMILES COc1ccc(cc1)-n1cc(COc2ccc(\C=C3/SC(=O)NC3=O)cc2)nn1

InChI Key InChIKey=QREHBNWFOKFYBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523303   

TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523303(CHEMBL4472170)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant COX2 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50523303(CHEMBL4472170)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed