BDBM50523278 CHEMBL4463060

SMILES [H][C@]12CCCCN1C(=O)c1cccc(NC(=O)Nc3cc(ccn3)C#C)c21

InChI Key InChIKey=WROPYEAREMSHKX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523278   

TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
Cnrs

Curated by ChEMBL

LigandBDBM50523278(CHEMBL4463060)Copy SMILESCopy InChI

Affinity DataIC50: 33nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetCyclin-dependent kinase 5 activator 1(Human)
Cnrs

Curated by ChEMBL

LigandBDBM50523278(CHEMBL4463060)Copy SMILESCopy InChI

Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL