BDBM50523273 CHEMBL4459540

SMILES O=C(Nc1cc(COCc2cn(CCNc3ccncc3)nn2)ccn1)Nc1cccc2C(=O)N3CCCCC3c12

InChI Key InChIKey=HPUUQGKVJFVXEY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523273   

TargetCyclin-dependent kinase 5 activator 1(Human)
Cnrs

Curated by ChEMBL

LigandBDBM50523273(CHEMBL4459540)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
Cnrs

Curated by ChEMBL

LigandBDBM50523273(CHEMBL4459540)Copy SMILESCopy InChI

Affinity DataIC50: 30nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL