BDBM50523095 CHEMBL4573441

SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccc(Cl)cn1

InChI Key InChIKey=MXKZBMGRCYCKSV-UHFFFAOYSA-N

Data  18 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50523095   

TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
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TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
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TargetSigma intracellular receptor 2(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  8.40nMAssay Description:Displacement [3H]-DTG from sigma 2 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetSigma intracellular receptor 2(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  8.5nMAssay Description:Displacement [3H]-DTG from sigma 2 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetSigma non-opioid intracellular receptor 1(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Displacement [3H]-Pentazocine from sigma 1 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetSigma non-opioid intracellular receptor 1(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Displacement [3H]-Pentazocine from sigma 1 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2021
Entry Details Article
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Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  34nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  34nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  46nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  46nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  86nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  87nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  207nMAssay Description:Displacement of [3H]-LSD from human 5HT7 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  209nMAssay Description:Displacement of [3H]-LSD from human 5HT7 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  287nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  288nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  1.54E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
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Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL

LigandBDBM50523095(CHEMBL4573441)Copy SMILESCopy InChI

Affinity DataKi:  1.55E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL