BDBM50522998 CHEMBL4549278

SMILES CCn1cnc2c(NCc3cccc(\C=C\C(=O)NO)c3)nc(nc12)N1CCOCC1

InChI Key InChIKey=RSHKUDAKRMLDCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522998   

TargetHistone deacetylase 1(Human)
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50522998(CHEMBL4549278)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-tagged HDAC1 expressed in baculovirus expression system using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50522998(CHEMBL4549278)
Affinity DataIC50: 56nMAssay Description:Inhibition of wild-type human N-terminal GST-tagged CDK2/cycA2 expressed in Sf21 insect cells using FAM-labelled substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed