BDBM50522742 CHEMBL4444522

SMILES [H][C@@]12CCN(CC1=CC)Cc1c([nH]c3ccccc13)C2=O

InChI Key InChIKey=DBGBUYFOJXOYNY-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50522742   

TargetMu-type opioid receptor(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50522742(CHEMBL4444522)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50522742(CHEMBL4444522)
Affinity DataIC50: 7.00E+4nMAssay Description:Displacement of [3H]-diprenorphine from MOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50522742(CHEMBL4444522)
Affinity DataIC50: 7.00E+4nMAssay Description:Displacement of [3H]-diprenorphin from human mu opioid receptor incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50522742(CHEMBL4444522)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP production by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed