BDBM50522610 CHEMBL4572891

SMILES COc1ccc(F)c(c1)-c1ccc2[C@@H](CCc2c1)Oc1cccc(c1)[C@@H]([C@H](C)C(O)=O)C1CC1

InChI Key InChIKey=ZKPORIQWWQUQHA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522610   

TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50522610(CHEMBL4572891)
Affinity DataEC50:  4.5nMAssay Description:Positive allosteric modulation of recombinant human GPR40 expressed in HEK293 cells assessed as increase in [3H]-myo-inositol phosphate accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50522610(CHEMBL4572891)
Affinity DataEC50:  388nMAssay Description:Positive allosteric modulation of recombinant human GPR40 expressed in HEK293 cells assessed as increase in [3H]-myo-inositol phosphate accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed