BDBM50522372 CHEMBL4473575

SMILES C[C@@]1(OC[C@@H](COc2ccc(cc2)N2CCN(CC2)c2ccc(cc2)-n2cn[nH]c2=O)O1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=YHGHBAXLVHCABI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522372   

TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522372(CHEMBL4473575)
Affinity DataIC50: 210nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed