BDBM50522144 CHEMBL4466864

SMILES COc1ccc(CNCc2ccc(\C=C\C(=O)NO)cc2)cc1OC

InChI Key InChIKey=HOTVLIFEMAJCSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50522144   

TargetHistone deacetylase 2(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human recombinant HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1/2/3/8(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 371nMAssay Description:Inhibition Class 1 histone deacetylase in human HeLa nuclear extracts using Fluor-de- Lys-green substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50522144(CHEMBL4466864)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed