BDBM50521869 CHEMBL4446268

SMILES Cc1cc(n2c(n1)nc(n2)CCNc3ccc4ccccc4n3)C

InChI Key InChIKey=GAAIMHFFJZPUGG-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521869   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50521869(CHEMBL4446268)Copy SMILESCopy InChI

Affinity DataIC50: 294nMAssay Description:Inhibition of human PDE10A using cAMP as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HTRF detecti...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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