BDBM50521207 CHEMBL4451278

SMILES Fc1cc(ccc1Cl)C(=O)Nc1cc2cc[nH]c2cn1

InChI Key InChIKey=VBEFQDCTDAFHBI-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50521207   

TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50521207(CHEMBL4451278)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50521207(CHEMBL4451278)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-A using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50521207(CHEMBL4451278)
Affinity DataIC50: 574nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-B using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50521207(CHEMBL4451278)
Affinity DataIC50: 121nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50521207(CHEMBL4451278)
Affinity DataKi:  54nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed