BDBM50520885 CHEMBL4521157

SMILES O=C(Oc1cccc(c1)C#N)N1CCC(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=GPWBPGWBQRHYDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520885   

TargetMonoglyceride lipase(Human)
Mak Scientific

Curated by ChEMBL
LigandPNGBDBM50520885(CHEMBL4521157)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant human His6-tagged MGL expressed in Escherichia coli BL21(DE3) cells using AHMMCE as substrate preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
Mak Scientific

Curated by ChEMBL
LigandPNGBDBM50520885(CHEMBL4521157)
Affinity DataIC50: 37nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Mak Scientific

Curated by ChEMBL
LigandPNGBDBM50520885(CHEMBL4521157)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat FAAH using AAMCA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed