BDBM50520833 CHEMBL4569077

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(cc2)\N=C2/C(=O)N(Cc3ccc(cc3)C#N)c3ccccc23)cc1

InChI Key InChIKey=PWDSWILKMGWZLG-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50520833   

TargetVascular endothelial growth factor receptor 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50520833(CHEMBL4569077)
Affinity DataIC50: 207nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) as substrate measured after 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50520833(CHEMBL4569077)
Affinity DataKi:  8.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50520833(CHEMBL4569077)
Affinity DataKi:  9.70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50520833(CHEMBL4569077)
Affinity DataKi:  77nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50520833(CHEMBL4569077)
Affinity DataKi:  2.29E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed