BDBM50520812 CHEMBL4446949

SMILES Fc1ccc(cc1)-c1cc(nc2c(cccc12)P(=O)(c1ccccc1)c1ccccc1)-c1ccc(F)c(F)c1

InChI Key InChIKey=DGFRGJSADOQCKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50520812   

TargetDNA topoisomerase 1(Human)
Universidad De Le£N

Curated by ChEMBL
LigandPNGBDBM50520812(CHEMBL4446949)
Affinity DataIC50: 6.97E+4nMAssay Description:Inhibition of human Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed