BDBM50520163 CHEMBL4524534

SMILES Cc1noc(n1)-c1ccc2nc(Nc3cc(ccn3)C(=O)N3CCN(CC3)C(=O)CC(F)(F)F)[nH]c2c1

InChI Key InChIKey=GVIREMXPPOOMKA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50520163   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50520163(CHEMBL4524534)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50520163(CHEMBL4524534)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520163(CHEMBL4524534)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520163(CHEMBL4524534)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed