BDBM50519953 CHEMBL2140832

SMILES COc1ccc(cc1S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F)C(O)=O

InChI Key InChIKey=NDYXAJZYGMHQDN-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50519953   

TargetEndoplasmic reticulum aminopeptidase 2(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP2 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using R-AMC as substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using WRCYEKMALK as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERAP1 in human HeLa cells stably expressing H-2 Kb infected with vaccinia virus containing ss-LEQLE-SIINFEKL epitope assessed as suppre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 2.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 2.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 5.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataKi:  3.80E+3nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed