BDBM50519927 CHEMBL4546925
SMILES [H][C@]12C[C@@H]([C@H](CC)CN1CCc1c2[nH]c2cccc(OC)c12)C(=C/OC)\C(=O)OC
InChI Key InChIKey=LELBFTMXCIIKKX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50519927
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DOP (unknown origin)More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataEC50: 1.36E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataEC50: 73nMAssay Description:Partial agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by sci...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KOP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MOP (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of cAMP accumulation incubated for 10 mins by...More data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cells incubated for 120 mins by radiometric scintillation ana...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Displacement of [3H]U69,593 from human recombinant kappa opioid receptor expressed in rat RBL cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 329nMAssay Description:Binding affinity to KOP (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 560nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: 649nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
University of Health Sciences & Pharmacy and Washington University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.15E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair