BDBM50519874 CHEMBL4582264

SMILES OC(=O)Cn1c2ccccc2c2n[nH]c(=O)nc12

InChI Key InChIKey=QCXGAVTUFVFJIT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50519874   

TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 292nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 42nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of human AKR1B10 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 216nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 66nMAssay Description:Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50: 51nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed