BDBM50519740 CHEMBL4528980

SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1ccc(OCCCCCN2CCCC2)cc1)C(=O)OCC

InChI Key InChIKey=FMYWPHYXKMHHNZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519740   

LigandPNGBDBM50519740(CHEMBL4528980)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
UBFC

Curated by ChEMBL
LigandPNGBDBM50519740(CHEMBL4528980)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of BuChE in human plasma using butyrylthiocholine iodide substrate by Ellman's protocol based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
UBFC

Curated by ChEMBL
LigandPNGBDBM50519740(CHEMBL4528980)
Affinity DataKi:  425nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed