BDBM50519728 CHEMBL4550794

SMILES Cc1nc(Nc2ncc(s2)-c2ccncc2)cc(n1)N1CCN(CCO)CC1

InChI Key InChIKey=YUFNNCBNQOTZPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519728   

TargetMast/stem cell growth factor receptor Kit(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50519728(CHEMBL4550794)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) (unknown origin) expressed in baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50519728(CHEMBL4550794)
Affinity DataIC50: 43nMAssay Description:Inhibition of wild type recombinant GST-tagged FLT3 (Y567 to S993 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed