BDBM50519707 CHEMBL4451007

SMILES CC(C)(C)c1cc(no1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1

InChI Key InChIKey=FJCVQMSTNYMHPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519707   

TargetRho-associated protein kinase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50519707(CHEMBL4451007)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human ROCK2 (11 to 552 residues) using KEAKEKRQEQIAKR as substrate incubated for 40 mins in presence of [gamma-33P]ATP and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50519707(CHEMBL4451007)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKR as substrate incubated for 40 mins in presence of [gamma-33P]ATP and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed