BDBM50519648 CHEMBL4441118

SMILES Cc1cc(-c2cnc(N)c3c(csc23)-c2ccc3scnc3c2)n(C)n1

InChI Key InChIKey=BPKSNNJTKPIZKR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50519648   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of GSK657 binding to human RIPK1 (1 to 328) by fluorescence Polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human RIPK1 by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human RIPK3 (2-328) residues expressed in baculovirus by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human RIPK3 (2-328) residues expressed in baculovirus by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519648(CHEMBL4441118)
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed