BDBM50519642 CHEMBL4469781

SMILES CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4ncsc4c3)c2c1

InChI Key InChIKey=XXUZHBQHZWBYMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519642   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519642(CHEMBL4469781)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human RIPK1 by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50519642(CHEMBL4469781)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of GSK657 binding to human RIPK1 (1 to 328) by fluorescence Polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed