BDBM50519619 CHEMBL4444429

SMILES Clc1ccc2c(CCC[C@]22COc3ccc4cc3N(C2)CCCCCCOCCS(=O)(=O)NC4=O)c1

InChI Key InChIKey=LHCTZVFESCSNEW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519619   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50519619(CHEMBL4444429)
Affinity DataIC50: 10nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetG1/S-specific cyclin-D1(Human)
Technical University of Darmstadt

Curated by ChEMBL
LigandPNGBDBM50519619(CHEMBL4444429)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed