BDBM50519596 CHEMBL4573293

SMILES C[C@H]1Oc2cc(Cc3c(C)nn(C)c3CN(C)C(=O)c3ccc(F)cc13)cnc2N

InChI Key InChIKey=UEPIXSNYZDRAQN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519596   

TargetALK tyrosine kinase receptor(Mouse)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50519596(CHEMBL4573293)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ALK in mouse NIH-3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50519596(CHEMBL4573293)
Affinity DataIC50: 14nMAssay Description:Inhibition of ALK L1196M (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50519596(CHEMBL4573293)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of ALK L1196M mutant in mouse NIH-3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed