BDBM50519564 CHEMBL4545127

SMILES Cc1cc(Nc2ccc(c(F)c2)S(F)(F)(F)(F)F)n2nc(nc2n1)C(C)(F)F

InChI Key InChIKey=NLEHXOQPQQDQBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519564   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519564(CHEMBL4545127)
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli using L-dihydroorotate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50519564(CHEMBL4545127)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human DHODH expressed in Escherichia coli using L-dihydroorotate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed