BDBM50519432 CHEMBL4469760

SMILES Fc1ccc(cc1)-c1c[nH]c2ccnc(Nc3ccc(Oc4ccnc(NC(=O)C5CCCCC5)c4)c(F)c3)c2c1=O

InChI Key InChIKey=KPMLCQPOXALFEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519432   

TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50519432(CHEMBL4469760)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of purified recombinant MET kinase domain (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50519432(CHEMBL4469760)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of purified recombinant VEGFR2 kinase domain (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed