BDBM50519412 CHEMBL4474399

SMILES Cc1ccc2oc(cc(=O)c2c1)-c1ccc(OCCCCCCN2CCCCC2)cc1

InChI Key InChIKey=NDDYCWJCTGXGIS-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50519412   

TargetAcetylcholinesterase(Electric eel)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataIC50: 500nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataIC50: 760nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataKi:  129nMAssay Description:Non-competitive inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataKi:  129nMAssay Description:Non-competitive inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50519412(CHEMBL4474399)
Affinity DataKi:  228nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human histamine H3 receptor stably expressed in HEK293 cell membrane after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed