BDBM50519196 CHEMBL4436134

SMILES Cc1c(ccc2c1OC(=O)C(=C2C)CC(=O)O)OCc3cccc(c3)C(F)(F)F

InChI Key InChIKey=NSSHMSRIOYOKOP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519196   

TargetChloride anion exchanger(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50519196(CHEMBL4436134)
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChloride anion exchanger(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50519196(CHEMBL4436134)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/bicarbonate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed