BDBM50518999 CHEMBL4441326

SMILES CN1[C@H](Cc2c[nH]c3c(cccc23)-c2cccc(c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C1=O)C(N)=O

InChI Key InChIKey=IGRZOKIVRZOBLQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50518999   

TargetIntegrin alpha-V/beta-3(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50518999(CHEMBL4441326)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human vitronectin binding to human integrin alphavbeta3 receptor after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50518999(CHEMBL4441326)
Affinity DataIC50: 547nMAssay Description:Inhibition of human fibronectin binding to human integrin alpha5beta1 incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50518999(CHEMBL4441326)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human fibronectin binding to human Integrin alpha2b beta3 receptor incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50518999(CHEMBL4441326)
Affinity DataIC50: 9.40E+3nMAssay Description:Binding affinity to integrin alphavbeta3 receptor in human WM115 cells assessed as inhibition of cell adhesion to vitronectin after 0.5 hr by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed