BDBM50518949 CHEMBL4448131

SMILES Fc1ccc2ccc(=O)n3C[C@@H](NCCC[C@H]4CN(C(=O)O4)c4ccc5OCC(=O)Nc5n4)c1c23

InChI Key InChIKey=GIYAXUINNMNECB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518949   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518949(CHEMBL4448131)
Affinity DataIC50: 125nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518949(CHEMBL4448131)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518949(CHEMBL4448131)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed