BDBM50518790 CHEMBL4465918

SMILES Oc1cc2N(C[C@@H](CCl)c2c2ccccc12)C(=O)CCCC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21

InChI Key InChIKey=PHWPEULWFLWFAR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50518790   

TargetVascular endothelial growth factor receptor 2(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR2 (D807 to V1356 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged c-KIT (T544 to V976 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAlcohol dehydrogenase 1A(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 460nMAssay Description:Inhibition of ADH1 (unknown origin) preincubated for 2 hrs followed by substrate/NAD+ additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged VEGFR3 (N799 to R1298 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL2(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 685nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged ABL2 (M1 to P650 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Albert Ludwigs University Freiburg

Curated by ChEMBL
LigandPNGBDBM50518790(CHEMBL4465918)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged VEGFR1 (K784 to I1338 residues) expressed in sf9 cells using Poly(Glu,Tyr) 4:1 as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed