BDBM50518676 CHEMBL4453888

SMILES [O-]C(=O)CSc1nnc(Br)n1Cc1ccc(Br)c2ccccc12

InChI Key InChIKey=CPIDEFQXIIQAOX-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518676   

TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518676BDBM50518676(CHEMBL4453888)
Affinity DataIC50: 94nMAssay Description:Inhibition of URAT1 (unknown origin) stably expressed in HEK293 cells assessed as reduction of uric acid uptake measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518676BDBM50518676(CHEMBL4453888)
Affinity DataIC50: 94nMAssay Description:Inhibition of human URAT1 stably expressed in HEK293 cells by measuring 14C-uric acid uptake pre-incubated for 15 mins followed by 14C-uric acid addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518676BDBM50518676(CHEMBL4453888)
Affinity DataIC50: 94nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed