BDBM50518598 CHEMBL4540950

SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=BLOFNYQHKSGSGE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518598   

TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50518598(CHEMBL4540950)
Affinity DataKi:  0.160nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged hepsin catalytic domain preincubated for 30 mins followed by Boc-QAR-AMC substrate addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50518598(CHEMBL4540950)
Affinity DataKi:  3.10nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli preincubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50518598(CHEMBL4540950)
Affinity DataKi:  33nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed