BDBM50518570 CHEMBL4462631

SMILES Cc1ccc(COC(=O)N(C2CN3CCC2CC3)c2ccccc2)cc1F

InChI Key InChIKey=UPDOKFNDDXFBCH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50518570   

TargetMuscarinic acetylcholine receptor M3(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50518570(CHEMBL4462631)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]NMS from human M3 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50518570(CHEMBL4462631)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50518570(CHEMBL4462631)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]NMS from human M2 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50518570(CHEMBL4462631)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]NMS from human M1 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed