BDBM50518536 CHEMBL4580973

SMILES CCCCC(CC)CN1C=NC2C1N=C(Cc1ccc(OCc3ccccc3)cc1)NC2=O

InChI Key InChIKey=TUERUXQAQDTRSA-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50518536   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of PDE9 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDE4 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDE1 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDE10 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 72nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Changzhou University

Curated by ChEMBL

LigandBDBM50518536(CHEMBL4580973)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PDE5 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL